Title

Stimulation of Glucose Oxidation in Rat Submandibular Gland Cells in Vitro by Analogues of Cyclic AMP

Document Type

Article

Publication Date

1985

Journal Title

Archives of Oral Biology

ISSN

0003-9969

Volume

30

Issue

9

First Page

701

Last Page

703

DOI

http://dx.doi.org/10.1016/0003-9969(85)90159-1

Abstract

Secretion from salivary glands, following autonomic stimulation, is energy-dependent. Rat submandibular gland cells, when treated in vitro with both alpha- and beta-adrenergic agonists, showed increased glucose oxidation. The effects of alpha-adrenergic agents on glucose metabolism can be mimicked by non-receptor mobilization of Ca2+. Analogues of cyclic AMP were capable of elevating glucose metabolism to nearly the same extent as beta-adrenergic agonists.

Keywords

Submandibular gland, salivary secretion, glucose, rats, cyclic AMP, stimulation, in vitro

PubMed ID

3000325