Engineering and Computer Science Faculty Presentations

Title

Nicotine Increases Osteoblast Activity in In Vitro Cell Culture in a Dose Dependent Manner

Document Type

Conference Presentation

Conference/Event

24th North American Spine Society (NASS) Annual Meeting

Location

San Francisco, CA

Event Date

11-10-2009

Abstract

BACKGROUND CONTEXT: Prior studies by our group have shown that nicotine delivered via a transdermal nicotine patch significantly enhanced posterior spinal fusion rates in rabbits. This runs contrary to previously published studies by other groups in which nicotine administration decreased fusion rates. Hence, there may be a dose-dependent effect of nicotine on posterior spinal fusion outcomes.

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