Apoptosis: Definition, Roles, and Regulation
The emergence of molecular biology, with the possibility of cloning genes and introducing them in cells where they are expressed, has challenged the classic concept of cell death. But that concept is still valid when defined as “a state in which cells are totally incapable of any function ... ”.1 That concept has been based mostly on morphological observation.
Rotello, Rocco J., "Apoptosis: Definition, Roles, and Regulation" (1993). Pharmaceutical Sciences Faculty Publications. 71.