Rat Parotid Cell Function in Vitro Following X Irradiation in Vivo
Document Type
Article
Publication Date
2-1984
Journal Title
Radiation Research
ISSN
0033-7587
Volume
97
Issue
2
First Page
386
Last Page
395
DOI
http://dx.doi.org/10.2307/3576289
Abstract
The effect of X irradiation on rat parotid acinar cell function was evaluated in vitro 1, 3, and 7 days following in vivo exposure to 2000 R. Several cellular functions were followed: protein secretion (amylase release), ion movement (K+ efflux and reuptake), amino acid transport (alpha-amino[14C]isobutyric acid), and an intermediary metabolic response ( [14C]glucose oxidation). In addition both the morphologic appearance and in vivo saliva secretory ability of parotid cells were assessed. Our results demonstrate that surviving rat parotid acinar cells, isolated and studied in vitro 1-7 days following 2000 R, remain functionally intact despite in vivo diminution of secretory function.
Keywords
Parotid gland, rats, amino acids, amylases, glucose, protein, irradiation, saliva secretion
PubMed ID
6198673
Recommended Citation
Bodner, L.; Kuyatt, Brian L.; Hand, A. R.; and Baum, B. J., "Rat Parotid Cell Function in Vitro Following X Irradiation in Vivo" (1984). Center for Teaching and Learning Publications. 9.
https://digitalcommons.cedarville.edu/ctl_publications/9
