Sheathless Electrospray Ionization Interfaces for Capillary Electrophoresis-Mass Spectrometric Detection Advantages and Limitations
Journal of Chromatography A
A review of sheathless interfaces for capillary electrophoresis (CE)-mass spectrometry (MS) is presented. The review discusses the on-line CE-MS system requirements, advantages and weaknesses of current sheathless interface designs for CE-electrospray ionization MS, and comparison between sheath flow and sheathless interfaces. The advantages and limitations of three sheathless designs are discussed and commented upon, these include single-capillary, two-capillary and three-piece designs.
Electrophoresis, capillary, spectrometry, mass, electrospray ionization
Issaq, Haleem J.; Janini, George M.; Chan, King C.; and Veenstra, Timothy D., "Sheathless Electrospray Ionization Interfaces for Capillary Electrophoresis-Mass Spectrometric Detection Advantages and Limitations" (2004). Pharmaceutical Sciences Faculty Publications. 442.