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VTE, PE, venous thromboembolism, pulmonary embolism


There is a discrepancy in the methods of prevention and treatment of VTE (venous thromboembolism). VTE is a first event in approximately 100 out of 100,000 people. VTE is the synthesis of DVT (deep vein thrombosis), which can ultimately lead to pulmonary embolism, and occurs when a clot forms in the peripheral veins, possibly dislodging and journeying to the lungs. PE (pulmonary embolism) is a blockage in an artery of the lungs and causes permanent tissue damage. 1 in 5 individuals with PE die almost immediately and a further 40% die within three months. PE can develop 3-7 days after diagnosis of deep vein thrombosis. A thrombus may possibly detach due to muscle contraction. Patients often die within one hour after symptoms appear. Traditionally, health care providers recommend bed rest, but prolonged bedridden time increases the risk of PE. The purpose of this study is to doscover what current research deems to be the evidence based practice concerning the use of bed rest compared with early ambulation when either method is combined with thrombolytic therapy in the prevention and treatment of VTE.

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