Rebecca J. Gryka, Pharm.D., Ph.D.; Denise Simpson, Ph.D.
Meropenem, nausea, pediatrics, cystic fibrosis
Cystic Fibrosis (CF) is a genetic disease, leading to changes of membrane secretions causing obstruction of smaller airways. CF patients often develop pulmonary infections and require antibiotic treatment. Meropenem is a broad spectrum beta lactam that acts by lysing microbes through interfering with bacterial cell wall synthesis. Although a safe and effective treatment, data on pediatric patients is limited.
Cushing, Marissa; Draime, Juanita A.; Ho, Bao-Ngoc; Nicholls, Jordan; Sibbitt, Bethany; Widder, Rebecca; Gryka, Rebecca J.; and Simpson, Denise S., "A Comparison of the Effect of Intermittent and Continuous Infusion of Meropenem on the Prevalence of Nausea in Pediatric Cystic Fibrosis Patients" (2012). Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session. 6.
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