•  
  •  
 

Abstract

A preliminary study was performed by Tomkins comparing 40,000 chimpanzee genomic sequences against the human genome which indicated that reported levels of human-chimp DNA similarity were significantly lower than commonly reported. The present, follow-up study was then completed in which chimp chromosomes were sliced into new individual query files of varying string lengths and queried against their human chromosome homolog. This allowed for comparisons to be optimized irrespective of the linear order of genes and sequence features. The definition of similarity was the amount (percent) of optimally aligned chimp DNA. For the chimp autosomes, the amount of optimally aligned DNA sequence provided similarities between 66 and 76 percent, depending on the chromosome. Only 69 percent of the chimpanzee X chromosome was similar to human and only 43 percent of the Y chromosome. Genome-wide, only 70% of the chimpanzee DNA was similar to human under the most optimal alignment conditions. While, chimpanzees and humans share many localized protein-coding regions of high similarity, the overall extreme discontinuity between the two genomes defies evolutionary time-scales and dogmatic presuppositions about a common ancestor.

Keywords

Human, Chimpanzee, Genome, DNA Similarity, Primate Evolution

Disclaimer

DigitalCommons@Cedarville provides a publication platform for fully open access journals, which means that all articles are available on the Internet to all users immediately upon publication. However, the opinions and sentiments expressed by the authors of articles published in our journals do not necessarily indicate the endorsement or reflect the views of DigitalCommons@Cedarville, the Centennial Library, or Cedarville University and its employees. The authors are solely responsible for the content of their work. Please address questions to dc@cedarville.edu.

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.