Addresses of All Authors
1806 Royal Lane, Dallas, TX 75229
Author's Biography
Jeffrey Tomkins is the Director of Life Sciences at the Institute for Creation Research (ICR). He has a Ph.D. in Genetics from Clemson University, an M.S. in Plant Science from the University of Idaho, and a B.S. in Agriculture Ed. from Washington State University. He was a faculty member in Genetics and Biochemistry at Clemson University for a decade, publishing 57 secular research papers and seven book chapters. Dr. Tomkins specializes in genomics and has published 27 peer-reviewed creation science journal papers, two books, and a wide variety of semi-technical articles in the ICR magazine Acts & Facts.
Proposal
Evolutionists allege that human chromosome 2 is the product of an ancient fusion event in an ancient hominid ancestor descended from apes. However, both the alleged site of fusion and the so-called cryptic centromere of human chromosome 2 are situated inside active genes negating the idea of fusion. Not only are the alleged genomic fossils of fusion representative of functional intragenic sequence, but they are also both highly degenerate versions of their supposed evolutionary beginnings, suggesting something other than an evolutionary origin. Given that these data strongly refute an evolutionary fusion scenario, it behooves creationists to propose an alternative model for the functional nature of telomere-like sequences scattered around the internal regions of human chromosomes. Towards this end, new data based on ENOCODE project data sets is provided that further elucidates the regulatory role of interstitial telomeric repeat sequences genome-wide, particularly with respect to their transcription factor binding domain properties and transcription start site associations.
Disciplines
Biology | Genomics
Keywords
Chromosome 2 fusion, DDX11L2 gene, ANKRD30BL transmembrane protein, human evolution, human-chimpanzee, cryptic centromere, interstitial telomere sequence, transcription factor binding, transcription start site
DOI
https://doi.org/10.15385/jpicc.2018.8.1.22
Print Reference
Pages 222-228
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Recommended Citation
Tomkins, J.P. 2018. Combinatorial genomic data refute the human chromosome 2 evolutionary fusion and build a model of functional design for interstitial telomeric repeats. In Proceedings of the Eighth International Conference on Creationism, ed. J.H. Whitmore, pp. 222–228. Pittsburgh, Pennsylvania: Creation Science Fellowship.
Tomkins 2018 ICC Proposal