Pharmaceutical Sciences Faculty Publications
Document Type
Article
Publication Date
6-5-2009
Journal Title
Genome Medicine
ISSN
1756-994X
Volume
1
Issue
6
First Page
58
Last Page
58
DOI
10.1186/gm58
PubMed ID
19519954
PubMed Central® ID
PMC2703867
Abstract
With the increase in technological capabilities for measuring biological molecules, there is a greater trend to conduct non-biased, discovery-driven studies that collect information on hundreds of molecules in a single study. The hope is that novel findings can be detected within these large datasets. For protein analysis, these non-biased studies are particularly challenging as no technology is presently capable of providing a view of the entire proteome. The ability of non-biased studies to accurately detect specific differences within the proteomes of samples obtained from differentially treated individuals must be conclusively demonstrated before investigators will routinely adopt these methods as part of their experimental protocols. This need is especially true for clinical and epidemiological studies in which limited amounts of samples are available.
Keywords
Global, proteomic, estrogen, therapy, proteins
Recommended Citation
Veenstra, Timothy D., "Using a Global Proteomic Approach to Identify Proteins Affected by Estrogen Therapy" (2009). Pharmaceutical Sciences Faculty Publications. 293.
https://digitalcommons.cedarville.edu/pharmaceutical_sciences_publications/293