Pharmaceutical Sciences Faculty Publications
Clinical Proteomic Applications of Formalin-Fixed Paraffin-Embedded Tissues
Document Type
Article
Publication Date
3-1-2009
Journal Title
Clinics in Laboratory Medicine
ISSN
1557-9832
Volume
29
Issue
1
First Page
101
Last Page
113
DOI
10.1016/j.cll.2009.01.006
PubMed ID
19389554
Abstract
Although proteomic technology has proved to be extremely powerful in basic research, its impact has not been as great in the clinical laboratory. The future, however, looks extremely positive because technologies, such as mass spectrometry and tissue microarrays, have continued to improve over the past several years. One of the most exciting developments, particularly in the area of mass spectrometry, is the ability to examine formalin-fixed paraffin-embedded tissue using these technologies. The almost inexhaustible supply of these tissues will enable proteomic laboratories access to clinically important specimens that will undoubtedly lead to a number of important discoveries in the near future.
Keywords
Biomarkers, formaldehyde, immunohistochemistry, mass spectrometry, neoplasms, paraffin embedding, proteomics, reproducibility of results, tissue array analysis
Recommended Citation
Blonder, Josip and Veenstra, Timothy D., "Clinical Proteomic Applications of Formalin-Fixed Paraffin-Embedded Tissues" (2009). Pharmaceutical Sciences Faculty Publications. 318.
https://digitalcommons.cedarville.edu/pharmaceutical_sciences_publications/318