Pharmaceutical Sciences Faculty Publications
Document Type
Article
Publication Date
4-1-2008
Journal Title
BioTechniques
ISSN
0736-6205
Volume
44
Issue
5
First Page
667
Last Page
668
DOI
10.2144/000112791
PubMed ID
18474043
Abstract
While definitely not a new technology, mass spectrometry (MS) has seen incredible growth over the past 25 years. Mass spectrometry has rapidly evolved to the forefront of analytical techniques; its ability to analyze proteins is the major driving force in the field of proteomics. MS instrumentation has increased approximately 5-fold in sensitivity every three years. The level of performance that is achievable with MS today allows scientists to study proteins in ways that were inconceivable a quarter century ago. This review of the history of MS over the past 25 years is timely in that it encompasses two of the biggest developments, electrospray and matrix-assisted laser desorption/ionization (MALDI), which have enabled many of the uses of this technology today.
Keywords
Mass spectrometry, peptide mapping, proteomics
Recommended Citation
Zhou, Ming and Veenstra, Timothy D., "Mass Spectrometry: M/Z 1983-2008" (2008). Pharmaceutical Sciences Faculty Publications. 327.
https://digitalcommons.cedarville.edu/pharmaceutical_sciences_publications/327