Pharmaceutical Sciences Faculty Publications
Biomarkers: Mining the Biofluid Proteome
Document Type
Article
Publication Date
4-1-2005
Journal Title
Molecular & Cellular Proteomics
ISSN
1535-9476
Volume
4
Issue
4
First Page
409
Last Page
418
DOI
10.1074/mcp.M500006-MCP200
PubMed ID
15684407
Abstract
Proteomics has brought with it the hope of identifying novel biomarkers for diseases such as cancer. This hope is built on the ability of proteomic technologies, such as mass spectrometry (MS), to identify hundreds of proteins in complex biofluids such as plasma and serum. There are many factors that make this research very challenging beginning with the lack of standardization of sample collection and continuing through the entire analytical process. Fortunately the advances made in the characterization of biofluids using proteomic techniques have been rapid and suggest that these mainly discovery driven approaches will lead to the development of highly specific platforms for diagnosing diseases and monitoring responses to different treatments in the near future.
Keywords
Biomarkers, blood proteins, humans, proteome, proteomics
Recommended Citation
Veenstra, Timothy D.; Conrads, Thomas P.; Hood, Brian L.; Avellino, Anthony M.; Ellenbogen, Richard G.; and Morrison, Richard S., "Biomarkers: Mining the Biofluid Proteome" (2005). Pharmaceutical Sciences Faculty Publications. 425.
https://digitalcommons.cedarville.edu/pharmaceutical_sciences_publications/425
