Pharmacy Practice Faculty Publications
Pharmacologic Management by Clinical Pharmacists of Behavioral and Psychological Symptoms of Dementia in Nursing Home Residents: Results from a Pilot Study
Document Type
Article
Publication Date
2-2003
Journal Title
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
ISSN
0277-0008
Volume
23
Issue
2
First Page
217
Last Page
221
DOI
http://dx.doi.org/10.1592/phco.23.2.217.32084
PubMed ID
12587811
Abstract
A pharmacist-based consulting service was developed for the pharmacologic management of behavioral and psychological symptoms of dementia (BPSD) in a nursing home setting. Patients were evaluated using the Behavioral Pathology in Alzheimer's Disease (BEHAVE-AD) rating scale, and pharmacotherapy was selected using a structured approach. Eleven patients were evaluated and treated with various psychotropic drugs. The most commonly administered drug was trazodone at a mean dosage of 70 mg/day (range 50–100 mg/day). Nine of the patients demonstrated satisfactory treatment responses as shown by a decreased BEHAVE-AD score of 30% or more (average BEHAVE-AD scores at baseline and 1 month after treatment were 13 ± 4 and 4 ± 3, respectively), and no clinical side effects were observed. The service was well received by the facility staff and primary care providers. These preliminary results suggest that pharmacists can play an important role in the pharmacotherapy of BPSD with positive clinical outcomes.
Keywords
Pharmacologic management, clinical pharmacists, dementia, nursing home, geriatric assessment, health services for the aged, New York, pharmacology, pilot projects, psychotropic drugs, trazodone
Recommended Citation
Rojas-Fernandez, Carlos H.; Eng, Marty L.; and Allie, Nicole D., "Pharmacologic Management by Clinical Pharmacists of Behavioral and Psychological Symptoms of Dementia in Nursing Home Residents: Results from a Pilot Study" (2003). Pharmacy Practice Faculty Publications. 88.
https://digitalcommons.cedarville.edu/pharmacy_practice_publications/88