Pharmacy Faculty Publications
Omics in Systems Biology: Current Progress and Future Outlook
Document Type
Article
Publication Date
2-2021
Journal Title
Proteomics
Volume
21
Issue
3-4
DOI
10.1002/pmic.202000235
Abstract
Biological research has undergone tremendous changes over the past three decades. Research used to almost exclusively focus on a single aspect of a single molecule per experiment. Modern technologies have enabled thousands of molecules to be simultaneously analyzed and the way that these molecules influence each other to be discerned. The change is so dramatic that it has given rise to a whole new descriptive suffix (i.e., omics) to describe these fields of study. While genomics was arguably the initial driver of this new trend, it quickly spread to other biological entities resulting in the creation of transcriptomics, proteomics, metabolomics, etc. The development of these “big four omics” created a wave of other omic fields, such as epigenomics, glycomics, lipidomics, microbiomics, and even foodomics; all with the purpose of comprehensively studying all the molecular entities or processes within their respective domain. The large number of omic fields that are invented even led to the term “panomics” as a way to classify them all under one category. Ultimately, all of these omic fields are setting the foundation for developing systems biology; in which the focus will be on determining the complex interactions that occur within biological systems.
Keywords
Proteomics, systems biology, research, omics, future, outlook
Recommended Citation
Veenstra, Timothy, "Omics in Systems Biology: Current Progress and Future Outlook" (2021). Pharmacy Faculty Publications. 27.
https://digitalcommons.cedarville.edu/pharmacy_publications/27