Pharmacy Faculty Research

 

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Research from 2014

A Pilot Study in Healthy Subjects to Quantitate Reductions in Pain Perception Following the Administration of OxyContin®, Jeffrey L. Huston

Research from 2013

A Single-Center, Randomized, Double-Blind Crossover Study to Evaluate the Abuse Potential, Pharmacokinetics, and Safety of Crushed and Intranasally Administered Immediate Release Oxycodone (OCI) Tablets in Recreational Opioid Users, Jeffrey L. Huston

Research from 2012

A Randomized, Open-Label, Crossover, Pilot Study in Healthy Subjects to Assess the Pharmacokinetics and Abuse-Deterrent Properties of Oxycodone Immediate-Release Formulations, Jeffrey L. Huston

Research from 2011

A Single-center, Randomized, Double-blind, Placebo-controlled, Escalating Single Dose Evaluation of the Safety, Tolerability, and Pharmacokinetics of V113741 in Healthy Males (POA1002), Jeffrey L. Huston

A Single-center, Randomized, Double-blind, Placebo-controlled, Escalating Single Dose Evaluation of the Safety, Tolerability, and Pharmacokinetics of V116517 in Healthy Males (VND1001), Jeffrey L. Huston

A Single-center, Randomized, Double-blind, Placebo-controlled, Escalating Single Dose Evaluation of the Safety, Tolerability, and Pharmacokinetics of V116517 in Healthy Males (VND1002), Jeffrey L. Huston

Phase I Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of N1814 Following Intramuscular Administration, Jeffrey L. Huston

Research from 2010

A Randomized Crossover Study to Evaluate the Pharmacokinetics of Hyoscyamine as Symax® DuoTab and as Symax® SL in Comparison with Hyoscyamine Sulfate Oral Solution (SOVCT-0024-001), Jeffrey L. Huston

Research from 2009

A Phase I Single-ascending-dose Crossover Study to Evaluate the Pharmacokinetics of N1539 Following Intravenous Administration (N1539-01), Jeffrey L. Huston

A Randomized, Placebo-controlled, Double-blind, Dose-escalation Phase I Study of the Safety, Tolerability and Pharmacokinetics of a Single Intravenous Dose of ETI-204 (AnthimTM) (AH-102), Jeffrey L. Huston

A Randomized, Single-blind, 3-way Crossover Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Crushed Intranasal Oxycodone Tamper Resistant Tablets (OTR) and OxyContinâ in Healthy Adults (OTR1021), Jeffrey L. Huston

A Randomized, Single-blind, Sequential Cohort, Crossover Study to Evaluate the Onset of Action of SKY0402 Following Local Infiltration in Healthy Volunteers (SKY0402-C-109), Jeffrey L. Huston

A Study in Type 2 Diabetic Subjects of Single and Multiple Doses of Orally Administered GSK1292263 to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of the Compound (GPR111598), Jeffrey L. Huston

Research from 2008

A Randomized, Double-blind Study to Evaluate and Compare the Pharmacokinetic and Pharmacodynamic Properties of Three Manufacturing Lots of SKY0402 Administered via Local Infiltration to Healthy Volunteers (SKY0402-C-108), Jeffrey L. Huston

A Single-center, Randomized, Double-blind, Placebo-controlled, Escalating Single Dose Evaluation of the Safety, Tolerability, and Pharmacokinetics of V113741 in Healthy Males (POA1001), Jeffrey L. Huston

Research from 2007

An Open-label, Randomized, Single Dose, Crossover Study to Assess the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Modified Release Formulations of GSK189075 in Healthy Volunteers (KGW111057), Jeffrey L. Huston

A Randomized, Single-blind, Crossover Study to Evaluate the Safety and Onset of Action of SKY0402 Following Subcutaneous Administration in Healthy Volunteers (SKY0402-C-106), Jeffrey L. Huston

The Pharmacokinetics and Safety of a Single Dose of SEP-225289 Administered With and Without Food in Healthy Volunteers (360-010), Jeffrey L. Huston

Research from 2006

A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of a Single Intravenous Dose of CBR-2092 in Healthy Volunteers (CBR-2092-001), Jeffrey L. Huston

A Randomized, Open-label, Single-dose, Four-way Crossover Pilot Study in Healthy Subjects to Assess the Pharmacokinetic Characteristics and Relative Bioavailability of Hydromorphone Following Administration of 3 Different Hydromorphone Tamper Resistant Formulations (12 mg) in the Fed and Fasted State, Compared to Palladone® (12 mg) in the Fed and Fasted State (HMP1017), Jeffrey L. Huston

Research from 2005

A Randomized, Placebo-controlled, Double-blind, Dose-escalation Phase I Study of the Safety, Tolerability and Pharmacokinetics of a Single Intravenous Dose of ETI-204 (AnthimTM) and its Potential Interaction with Ciprofloxacin (AH-101), Jeffrey L. Huston

Research from 2004

A Single-center, Open-label, Randomized Investigation in Healthy Volunteers to Determine the Intranasal Bioavailability of Naltrexone in a Three-way Crossover Study (OCX1009), Jeffrey L. Huston

A Single-center, Randomized, Double-blind, Placebo-controlled, Escalating Single Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of a V112054 Liquid Oral Formulation Following in Healthy Male Adults (CSB1001), Jeffrey L. Huston

Research from 2003

A Single-center, Randomized, Double-blind, Placebo-controlled, Escalating Single Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of a V134444 Oral Suspension Following AM Administration in Healthy Male Adults (CSH1001), Jeffrey L. Huston

Research from 2002

Tolerability of Oral Naltrexone in Patients Receiving OxyContin (OCX1001), Jeffrey L. Huston