Science and Mathematics Faculty Patents
Combination Therapy and Methods for Treating Bacterial Biofilms
Document Type
Patent
Publication Date
10-8-2013
Patent Number
US8551456B2
Abstract
A combination therapy for treating a bacterial biofilm comprises a therapeutically effective amount of an antibiotic comprising an aminoglycoside or tetracycline, or a combination of two or more thereof, and a cationic porphyrin in an amount effective for enhancing the effectiveness of the antibiotic in treating the bacterial biofilm. A method of treating a bacterial biofilm comprising Pseudomonas aeruginosa comprises contacting the bacterial biofilm with a combination therapy comprising a therapeutically effective amount of an antibiotic, and a cationic porphyrin in an amount effective for enhancing the effectiveness of the antibiotic in treating the bacterial biofilm. A method of treating a bacterial biofilm comprising Pseudomonas aeruginosa in a patient comprises administering to the patient a combination therapy comprising a therapeutically effective amount of an antibiotic, and a cationic porphyrin in an amount effective for enhancing the effectiveness of the antibiotic in treating the bacterial biofilm.
Recommended Citation
Robinson, Jayne B. and Collins, Tracy L., "Combination Therapy and Methods for Treating Bacterial Biofilms" (2013). Science and Mathematics Faculty Patents. 4.
https://digitalcommons.cedarville.edu/science_and_mathematics_patents/4
