Evaluating the Use of 5 Percent Human Albumin vs. Normal Saline for the Treatment of Hypotensive Crisis in Postoperative Patients

Presenters

Katherine Marshall, Cedarville University
Rachel Parrill, Cedarville University
Amy Voris, Cedarville University

Type of Submission

Poster

Keywords

Hypotension, postoperative patients, albumin

Campus Venue

Dixon Ministry Center, Alumni Hall

Location

Cedarville, OH

Start Date

4-10-2013 1:00 PM

End Date

4-10-2013 5:00 PM

Comments

Abstract:

Human albumin solutions and saline solutions are used frequently in emergent and post-sugical patients to stabilize extreme hypotension due to fluid loss. The problem that surrounds this project is that 5 percent human album in solution is being used as a resuscitative treatment for hypotension while exposing patients to additional risks as opposed to normal saline which has been found to be at least as effective as 5 percent human albumin solution at treating hypotension (Roberts, et al., 2011). A second consideration in the use of human albumin versus normal saline is cost. The cost of one 250 ml vial of 5 percent human albumin is $41.00 (FFF Enterprises, 2011). The cost of one 250 ml bag of 0.9 percent normal saline is $1.30 (PM I, 2012). At this cost ratio, over 31 bags of 0.9 percent normal saline could be purchased and safely used to provide patient care for the cost of one 250m I vial of 5 percent human albumin. In order for nurses to operate from an evidence-based perspective, we need to be aware of how to Introduce, develop and evaluate evidence-based practice. For this project, the current research related to the effect of human albumin vs. normal saline in post-surgical patients who experience extreme hypotension will be reviewed. This comprehensive review of the literature will be the basis for the development of an evidence-based policy for surgeons to consider.

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