Pharmacy Faculty Publications

 

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Publications from 2007

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CK2 Is a Component of the KSR1 Scaffold Complex that Contributes to Raf Kinase Activation, Daniel A. Ritt, Ming Zhou, Thomas P. Conrads, Timothy D. Veenstra, Terry D. Copeland, and Deborah K. Morrison

Targeting and Insertion of the Cholesterol-Binding Translocator Protein into the outer Mitochondrial Membrane, Malena B. Rone, Jun Liu, Josip Blonder, Xiaoying Ye, Timothy D. Veenstra, and Vassilios Papadopoulos

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Lower Levels of Urinary 2-Hhydroxyestrogens in Polycystic Ovary Syndrome, Sana Salih, Xia Xu, Timothy D. Veenstra, Antoni J. Duleba, Hala Fouad, Manubai Nagamani, and Ayman Al-Hendy

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Postnatal Maturation Modulates Relationships Among Cytosolic Ca2+, Myosin Light Chain Phosphorylation, and Contractile Tone in Ovine Cerebral Arteries, Renan J. Sandoval, Elisha R. Injeti, William T. Gerthoffer, and William J. Pearce

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Myogenic Contractility is More Dependent on Myofilament Calcium Sensitization in Term Fetal than Adult Ovine Cerebral Arteries, Renan J. Sandoval, Elisha R. Injeti, James M. Williams, William T. Gerthoffer, and William J. Pearce

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Prostaglandin E2 is a Major Inhibitor of Dendritic Cell Maturation and Function in Ixodes Scapularis Saliva, Anderson Sá-Nunes, André Bafica, David A. Lucas, Thomas P. Conrads, Timothy D. Veenstra, John F. Andersen, Thomas N. Mather, José M.C. Ribeiro, and Ivo M.B. Francischetti

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A Mutation in the SH2 domain of STAT2 prolongs tyrosine phosphorylation of STAT1 and promotes type I IFN-induced apoptosis., Anthony J. Scarzello, Ana L. Romero-Weaver, Stephen G. Maher, Timothy D. Veenstra, Ming Zhou, Angel Qin, Raymond P. Donnelly, Faruk Sheikh, and Ana M. Gamero

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Acetaminophen Usage Patterns and Concentrations of Glutathione and γ-Glutamyl Transferase in Alcoholic Subjects, C. F. Seifert and Douglas C. Anderson

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Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Preparation and Opioid Receptor Activity of Salvinicin Analogues, Denise S. Simpson, Peter L. Katavic, Anthony Lozama, Wayne W. Harding, Damon Parrish, Jeffrey R. Deschamps, Christina M. Dersch, John S. Partilla, Richard B. Rothman, Hernan Navarro, and Thomas E. Prisinzano

The Approach and Design of a Surrogate Protease Substrate for Disease Biomarker Discovery, Nicolas A. Stewart, Darue A. Prieto, Louis M. Cosentino, Haleem J. Issaq, and Timothy D. Veenstra

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A Blessing in Disguise, Dennis M. Sullivan

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Book Review: Genetics, Dennis M. Sullivan

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Book Review: The Language of God, Dennis M. Sullivan

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Making Sense of the Stem Cell Controversy, Dennis M. Sullivan

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Reproductive Technologies 101, Dennis M. Sullivan

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Under the Night Sky, Dennis M. Sullivan

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Gene Therapy: Restoring Health or Playing God?, Dennis M. Sullivan and Susan A. Salladay

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Sorting Through the Stem Cell Hype, Dennis M. Sullivan and Kathy Schoonover-Shoffner

Becoming an Exceptional Ohio Preceptor: More Than Being Experienced, Marc A. Sweeney

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The Ubiquitin Ligase gp78 Promotes Sarcoma Metastasis by Targeting KAI1 for Degradation, Yien Che Tsai, Arnulfo Mendoza, Jennifer M Mariano, Ming Zhou, Zlatka Kostova, Bo Chen, Timothy D. Veenstra, Stephen M. Hewitt, Lee J. Helman, Chand Khanna, and Allan M. Weissman

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The Protein Kinase C-η Isoform Induces Proliferation in Glioblastoma Cell Lines Through an ERK/Elk-1 Pathway, R. M. Uht, Samson Amos, P. M. Martin, A. E. Riggan, and Isa M. Hussaini

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Global and Targeted Quantitative Proteomics for Biomarker Discovery, Timothy D. Veenstra

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Analysis of the Extracellular Matrix Vesicle Proteome in Mineralizing Osteoblasts, Zhen Xiao, Corinne E. Camalier, Kunio Nagashima, King C. Chan, David A. Lucas, M. Jason de la Cruz, Michelle Gignac, Stephen Lockett, Haleem J. Issaq, Timothy D. Veenstra, and et al

A Liquid Chromatography-Mass Spectrometry Method for the Quantitative Analysis of Urinary Endogenous Estrogen Metabolites, Xia Xu, Larry K. Keefer, Regina G. Ziegler, and Timothy D. Veenstra

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Quantitative Measurement of Endogenous Estrogens and Estrogen Metabolites in Human Serum by Liquid Chromatography-Tandem Mass Spectrometry, Xia Xu, John M. Roman, Haleem J. Issaq, Larry K. Keefer, Timothy D. Veenstra, and Regina G. Ziegler

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Quantitative Proteomic Analysis of Human Breast Epithelial Cells with Differential Telomere Length, Li-Rong Yu, King C. Chan, Hidetoshi Tahara, David A. Lucas, Koushik Chatterjee, Haleem J. Issaq, and Timothy D. Veenstra

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Phosphoproteomics for the Discovery of Kinases as Cancer Biomarkers and Drug Targets, Li-Rong Yu, Haleem J. Issaq, and Timothy D. Veenstra

AACR–FDA–NCI Cancer Biomarkers Collaborative, Li-Rong Yu and Timothy D. Veenstra

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Improved Titanium Dioxide Enrichment of Phosphopeptides from HeLa Cells and High Confident Phosphopeptide Identification by Cross-Validation of MS/MS and MS/MS/MS Spectra, Li-Rong Yu, Zhongyu Zhu, King C. Chan, Haleem J. Issaq, Dimiter S. Dimitrov, and Timothy D. Veenstra

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Detection of In Vitro Kinase Generated Protein Phosphorylation Sites Using Gamma[18O4]-ATP and Mass Spectrometry, Ming Zhou, Zhaojing Meng, Andrew G. Jobson, Yves Pommier, and Timothy D. Veenstra

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Proteomic Analysis of Protein Complexes, Ming Zhou and Timothy D. Veenstra

Proteomic Analysis of Protein Complexes, M. Zhou and Timothy D. Veenstra

Publications from 2006

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Depression in Older Adults: The Case of an 82-year-old Woman with Dizziness, Ali Ahmed, Mark J. Yaffe, Phillip L. Thornton, and F. Cleveland Kinney

Plasma Proteomic Profiling: Search for Lung Cancer Diagnostic and Early Detection Markers, Iqbal Unnisa Ali, Zhen Xiao, Winfred Malone, Mylinh Smith, Thomas P. Conrads, Timothy D. Veenstra, Peter Greenwald, Brian T. Luke, and Jerry W. McLarty

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Protein Kinase C-α Mediated Downregulation of Low-Density Lipoprotein Receptor-related Protein Expression Increases Urokinase Secretion and Astrocytoma Invasion, Samson Amos and Isa M. Hussaini

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Farnesylthiosalicylic Acid Induces Caspase Activation and Apoptosis in Glioblastoma Cells, Samson Amos, G. T. Redpath, G. Polar, R. McPheson, D. Schiff, and I. M. Hussaini

Serevent, Advair, and the Black Box Warning, Douglas C. Anderson

Vancomycin Shortage, Douglas C. Anderson

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A Survey to Determine Influences on Pharmacy Students' Choice of Pharmacy as a Major, Douglas C. Anderson, M. C. Sheffield, A. M. Massey, and H. H. Cobb

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Direct Phosphorylation and Activation of a Nim1-Related Kinase Gin4 by Elm1 in Budding Yeast, Satoshi Asano, Jung-Eun Park, Li-Rong Yu, Ming Zhou, Krisada Sakchaisri, Chong J. Park, Young H. Kang, Jeremy Thorner, Timothy D. Veenstra, and Kyung S. Lee

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The Effects of Methimazole on Circulating Thyroid Hormone Levels in Sprague-Dawley Rats, Melissa J. Beck, D. A. Donahue, J. S. Varsho, M. D. Nemec, D. G. Stump, and J. F. Holson

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The Ontogeny of Circulating Thyroid Hormone Levels in Sprague-Dawley Rats, Melissa J. Beck, H. Fillutzy, J. Godsey, M. D. Nemec, D. G. Stump, and J. F. Holson

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A Pre- and Postnatal Study of Bicifadine HCl in Rats, Melissa J. Beck, J. P. Tizzano, P. A. Krieter, S. Ho, D. W. Sved, and J. Buelke-Sam

Identification of Membrane Proteins From Mammalian Cell/Tissue Using Methanol-Facilitated Solubilization and Tryptic Digestion Coupled with 2D-LC-MS/MS, Josip Blonder, King C. Chan, Haleem J. Issaq, and Timothy D. Veenstra

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Proteomic Profiling of Differentiating Osteoblasts, Josip Blonder, Zhen Xiao, and Timothy D. Veenstra

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Combined Chemical and Enzymatic Stable Isotope Labeling for Quantitative Profiling of Detergent-Insoluble Membrane Proteins Isolated Using Triton X-100 and Brij-96, Josip Blonder, Li-Rong Yu, Galina Radeva, King C. Chan, David A. Lucas, Timothy J. Waybright, Haleem J. Issaq, Frances J. Sharom, and Timothy D. Veenstra

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Proteomic and Biochemical Analysis of Purified Human Immunodeficiency Virus Type 1 Produced from Infected Monocyte-Derived Macrophages, Elena Chertova, Lori V. Coren, James D. Roser, Charles M. Trubey, Raymond C. Sowder, Eugene Barsov, Brian L. Hood, Robert J. Fisher, Thomas P. Conrads, Timothy D. Veenstra, and et al

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Mass Spectrometric Characterization of Post-Translational Modifications, Thomas P. Conrads, Brian L. Hood, and Timothy D. Veenstra

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Sampling and Analytical Strategies for Biomarker Discovery Using Mass Spectrometry, Thomas P. Conrads, Brian L. Hood, and Timothy D. Veenstra

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CKAP4/p63 is a Receptor for the Frizzled-8 Protein-Related Antiproliferative Factor from Interstitial Cystitis Patients, Thomas P. Conrads, Gillian M. Tocci, Brian L. Hood, Chen-Ou Zhang, Li Guo, Kristopher R. Koch, Christopher J. Michejda, Timothy D. Veenstra, and Susan K. Keay

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2-Cyano-3,12-Dioxooleana-1,9(11)-Diene-28-Oic Acid Disrupts Microtubule Polymerization: A Possible Mechanism Contributing to Apoptosis, Robin D. Couch, Neil J. Ganem, Ming Zhou, Veljko M. Popov, Tadashi Honda, Timothy D. Veenstra, Michael B. Sporn, and Amy C. Anderson

Let the Adventure Begin, Marty L. Eng

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Open-Label Trial Regarding the Use of Acupuncture and Yin Tui Na in Parkinson's Disease Outpatients: A Pilot Study on Efficacy, Tolerability, and Quality of Life, Marty L. Eng, K. E. Lyons, M. S. Greene, and R. Pahwa

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Prevalence of Bone Mineral Density Screening in Parkinson Disease Clinic Outpatients, Marty L. Eng, Kelly E. Lyons, and Rajesh Pahwa

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Polo-Like Kinase 1-Mediated Phosphorylation of the GTP-Binding Protein Ran is Important for Bipolar Spindle Formation, Yang Feng, Jin Hui Yuan, Sharon C. Maloid, Rebecca Fisher, Terry D. Copeland, Dan L. Longo, Thomas P. Conrads, Timothy D. Veenstra, Andrea Ferris, Steve Hughes, Dimiter S. Dimitrov, and Douglass K. Ferris

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Mass Spectrometry Reveals Specific and Global Molecular Transformations during Viral Infection, Eden P. Go, William R. Wikoff, Zhouxin Shen, Grace O'Maille, Hirotoshi Morita, Thomas P. Conrads, Anders Nordstrom, Sunia A. Trauger, Wilasinee Uritboonthai, Timothy D. Veenstra, and et al

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Regulation of Androgen Receptor Activity by Tyrosine Phosphorylation, Zhiyong Guo, Bojie Dai, Tianyun Jiang, Kexin Xu, Yingqiu Xie, Oekyung Kim, Issa Nesheiwat, Xiangtian Kong, Jonathan Melamed, Venkatesh D. Handratta, Vincent C.O. Njar, Angela M.H. Brodie, Li-Rong Yu, Timothy D. Veenstra, Hegang Chen, and Yun Qiu

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Cytokinesis Regulator ECT2 Changes its Conformation Through Phosphorylation at Thr-341 in G2/M Phase, T. Hara, M. Abe, H. Inoue, L.R. Yu, Timothy D. Veenstra, Y. H. Kang, K. S. Lee, and T. Miki

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A Validation of Place Preference Conditioning to Measure the Rewarding Properties of Drugs in Rats, M. T. Herberth, P. B. Bucci, C. Hutchison, Melissa J. Beck, M. D. Nemec, and G. J. Schaefer

Seniors' Attitudes and Knowledge About Medicare Part D, Aleda M. Hess and D. L. Sullivan

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Mass Spectrometric Analysis of Formalin-Fixed Paraffin-Embedded Tissue: Unlocking the Proteome Within, Brian L. Hood, Thomas P. Conrads, and Timothy D. Veenstra

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Unravelling the Proteome of Formalin-Fixed Paraffin-Embedded Tissue, Brian L. Hood, Thomas P. Conrads, and Timothy D. Veenstra

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Self-Regulated Plk1 Recruitment to Kinetochores by the Plk1-PBIP1 Interaction is Critical for Proper Chromosome Segregation, Young H. Kang, Jung-Eun Park, Li-Rong Yu, Nak-Kyun Soung, Sang-Moon Yun, Jeong K. Bang, Yeon-Sun Seong, Hongtao Yu, Susan Garfield, Timothy D. Veenstra, and Kyung S. Lee

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Increased Oxidation and Degradation of Cytosolic Proteins in Alcohol-Exposed Mouse Liver and Hepatoma Cells, Bong-Jo Kim, Brian L. Hood, Richard A. Aragon, James P. Hardwick, Thomas P. Conrads, Timothy D. Veenstra, and Byoung J. Song

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Potential Applications and Limitations of Proteomics in the Study of Neurological Disease, Yoshito Kinoshita, Takuma Uo, Suman Jayadev, Gwenn A. Garden, Thomas P. Conrads, Timothy D. Veenstra, and Richard S. Morrison

Proteomics in Models of Neurodegeneration, Y. Kinoshita, T. Uo, T. P. Conrads, Timothy D. Veenstra, and R. S. Morrison

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Deamidation of Peptides in Aerobic Nitric Oxide Solution by a Nitrosative Pathway, Li Kong, Joseph E. Saavedra, Gregory S. Buzard, Xia Xu, Brian L. Hood, Thomas P. Conrads, Timothy D. Veenstra, and Larry K. Keefer

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Probing Early Growth Response 1 Interacting Proteins at the Active Promoter in Osteoblast Cells Using Oligoprecipitation and Mass Spectrometry, Zhaojing Meng, Corinne E. Camalier, David A. Lucas, Timothy D. Veenstra, George R. Beck, and Thomas P. Conrads

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Inactivation of Oxidized and S-Nitrosylated Mitochondrial Proteins in Alcoholic Fatty Liver of Rats, Kwan-Hoon Moon, Brian L. Hood, Bong-Jo Kim, James P. Hardwick, Thomas P. Conrads, Timothy D. Veenstra, and Byoung J. Song

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Identification of Sokotrasterol Sulfate as a Novel Proangiogenic Steroid, Siun Murphy, Bruno Larrivée, Ingrid Pollet, Kyle S. Craig, David E. Williams, Xin-Hui Huang, Megan Abbott, Fred Wong, Cameron Curtis, Timothy D. Veenstra, and et al

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Proteomic Analysis of Plasma Membrane from Hypoxia-Adapted Malignant Melanoma, Luke H. Stockwin, Josip Blonder, Maja A. Bumke, David A. Lucas, King C. Chan, Thomas P. Conrads, Haleem J. Issaq, Timothy D. Veenstra, Dianne L. Newton, and Susanna M. Rybak

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End of Life Decisions 101, Dennis M. Sullivan

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Stem Cell Research and Moral Complicity, Dennis M. Sullivan

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Stem Cells 101, Dennis M. Sullivan

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The Oral Contraceptive as Abortifacient: An Analysis of the Evidence, Dennis M. Sullivan

Avoid Medicine Mishaps, Marc A. Sweeney and D. Conway

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Automation in Proteomics, Timothy D. Veenstra

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Mass Spectrometry: The Foundation of Proteomics, Timothy D. Veenstra

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Proteomic Approaches in Drug Discovery, Timothy D. Veenstra

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LC‐MS in Metabonomics: Optimization of Experimental Conditions for the Analysis of Metabolites in Human Urine, Timothy J. Waybright, Que N. Van, Gary M. Muschik, Thomas P. Conrads, Timothy D. Veenstra, and Haleem J. Issaq

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Chronic Hypoxic Decreases in Soluble Guanylate Cyclase Protein and Enzyme Activity are Age Dependent in Fetal and Adult Ovine Carotid Arteries, James M. Williams, Charles R. White, Melody M. Chang, Elisha R. Injeti, Lubo Zhang, and William J. Pearce

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Analysis of Fifteen Estrogen Metabolites Using Packed Column Supercritical Fluid Chromatography-Mass Spectrometry, Xia Xu, John M. Roman, Timothy D. Veenstra, Jennifer Van Anda, Regina G. Ziegler, and Haleem J. Issaq

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Parallel Analysis of Transcript and Translation Profiles: Identification of Metastasis-Related Signal Pathways Differentially Regulated by Drug and Genetic Modifications, Haiyan Yang, Li-Rong Yu, Ming Yi, David A. Lucas, Luanne Lukes, Mindy Lancaster, King C. Chan, Haleem J. Issaq, Robert M. Stephens, Timothy D. Veenstra, and et al

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Identification of the SELDI ProteinChip Human Serum Retentate by Microcapillary Liquid Chromatography-Tandem Mass Spectrometry, Ming Zhou, DaRue A. Prieto, David A. Lucas, King C. Chan, Haleem J. Issaq, Timothy D. Veenstra, and Thomas P. Conrads

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Multiplexed Immunofluorescence Microscopy for the Interrogation of Cellular Protein Complexes, Ming Zhou and Timothy Veenstra

Publications from 2005

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Phorbol 12-Myristate 13-Acetate Induces Epidermal Growth Factor Receptor Transactivation via Protein Kinase Cdelta/c-Src Pathways in Glioblastoma Cells, Samson Amos, Patrick M. Martin, Gregory A. Polar, Sarah J. Parsons, and Isa M. Hussaini

ACEI and ARB Conversion, Douglas C. Anderson

Herbal Medicines: Myths, Truths, and Clinical Trials, Douglas C. Anderson

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Pharmacologic Prevention or Delay of Type 2 Diabetes Mellitus, Douglas C. Anderson

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Concerted Mechanism of Swe1/Wee1 Regulation by Multiple Kinases in Budding Yeast, Satoshi Asano, Jung-Eun Park, Krisada Sakchaisri, Li-Rong Yu, Sukgil Song, Porntip Supavilai, Timothy Veenstra, and Kyung S. Lee

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Predicting Inhibitory Drug—Drug Interactions and Evaluating Drug Interaction Reports Using Inhibition Constants, Kenneth A. Bachmann and Jeffrey D. Lewis

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A Method for Simultaneous Whole-Body Inhalational (Inh.) Exposure of Lactating Rats and Offspring, Melissa J. Beck, M. D. Nemec, D Kirkpatrick, J. F. Holson, S. A. Lewis, V. J. Piccirillo, and D. McAllister

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Quantitative Profiling of the Detergent-Resistant Membrane Proteome of Iota-B Toxin Induced Vero Cells, Josip Blonder, Martha L. Hale, King C. Chan, Li-Rong Yu, David A. Lucas, Thomas P. Conrads, Ming Zhou, Michel R. Popoff, Haleem J. Issaq, Timothy D. Veenstra, and et al

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Low Molecular Weight Proteomic Information Distinguishes Metastatic from Benign Pheochromocytoma, F. M. Brouwers, E. F. Petricoin, L. Ksinantova, J. Breza, V. Rajapakse, S. Ross, D. Johann, M. Mannelli, B. L. Shulkin, Timothy D. Veenstra, and et al

Enrichment of Low-Molecular-Weight Proteins from Biofluids for Biomarker Discovery, Oleg Chertov, John T. Simpson, Arya Biragyn, Thomas P. Conrads, Timothy D. Veenstra, and Robert J. Fisher

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A Combined Proteome and Microarray Investigation of Inorganic Phosphate-Induced Pre-Osteoblast Cells, Kelly A. Conrads, Ming Yi, Kerri A. Simpson, David A. Lucas, Corinne E. Camalier, Li-Rong Yu, Timothy D. Veenstra, Robert M. Stephens, Thomas P. Conrads, and George R. Beck

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Cancer Proteomics: Many Technologies, One Goal, Thomas P. Conrads, Brian L. Hood, Emmanuel F. Petricoin, Lance A. Liotta, and Timothy D. Veenstra

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What Have We Learned from Proteomic Studies of Serum?, Thomas P. Conrads and Timothy D. Veenstra

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Mass Spectrometry Based Proteomic Approaches for Disease Diagnosis and Biomarker Discovery, T. P. Conrads, H. J. Issaq, J. Blonder, and Timothy D. Veenstra

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Developmental Neurotoxicity Study of Styrene by Inhalation in Crl-CD Rats, G. Cruzan, W. D. Faber, K. A. Johnson, L. S. Roberts, J. Hellwig, J. Maurissen, Melissa J. Beck, A. Radovsky, and D. G. Stump