Pharmacy Faculty Publications
Publications from 2007
The Search for Protein Biomarkers of Neurological Diseases, G. Muschik, H. J. Issaq, and Timothy D. Veenstra
CK2 Is a Component of the KSR1 Scaffold Complex that Contributes to Raf Kinase Activation, Daniel A. Ritt, Ming Zhou, Thomas P. Conrads, Timothy D. Veenstra, Terry D. Copeland, and Deborah K. Morrison
Targeting and Insertion of the Cholesterol-Binding Translocator Protein into the outer Mitochondrial Membrane, Malena B. Rone, Jun Liu, Josip Blonder, Xiaoying Ye, Timothy D. Veenstra, and Vassilios Papadopoulos
Lower Levels of Urinary 2-Hhydroxyestrogens in Polycystic Ovary Syndrome, Sana Salih, Xia Xu, Timothy D. Veenstra, Antoni J. Duleba, Hala Fouad, Manubai Nagamani, and Ayman Al-Hendy
Postnatal Maturation Modulates Relationships Among Cytosolic Ca2+, Myosin Light Chain Phosphorylation, and Contractile Tone in Ovine Cerebral Arteries, Renan J. Sandoval, Elisha R. Injeti, William T. Gerthoffer, and William J. Pearce
Myogenic Contractility is More Dependent on Myofilament Calcium Sensitization in Term Fetal than Adult Ovine Cerebral Arteries, Renan J. Sandoval, Elisha R. Injeti, James M. Williams, William T. Gerthoffer, and William J. Pearce
Prostaglandin E2 is a Major Inhibitor of Dendritic Cell Maturation and Function in Ixodes Scapularis Saliva, Anderson Sá-Nunes, André Bafica, David A. Lucas, Thomas P. Conrads, Timothy D. Veenstra, John F. Andersen, Thomas N. Mather, José M.C. Ribeiro, and Ivo M.B. Francischetti
A Mutation in the SH2 domain of STAT2 prolongs tyrosine phosphorylation of STAT1 and promotes type I IFN-induced apoptosis., Anthony J. Scarzello, Ana L. Romero-Weaver, Stephen G. Maher, Timothy D. Veenstra, Ming Zhou, Angel Qin, Raymond P. Donnelly, Faruk Sheikh, and Ana M. Gamero
Acetaminophen Usage Patterns and Concentrations of Glutathione and γ-Glutamyl Transferase in Alcoholic Subjects, C. F. Seifert and Douglas C. Anderson
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Preparation and Opioid Receptor Activity of Salvinicin Analogues, Denise S. Simpson, Peter L. Katavic, Anthony Lozama, Wayne W. Harding, Damon Parrish, Jeffrey R. Deschamps, Christina M. Dersch, John S. Partilla, Richard B. Rothman, Hernan Navarro, and Thomas E. Prisinzano
The Approach and Design of a Surrogate Protease Substrate for Disease Biomarker Discovery, Nicolas A. Stewart, Darue A. Prieto, Louis M. Cosentino, Haleem J. Issaq, and Timothy D. Veenstra
A Blessing in Disguise, Dennis M. Sullivan
Book Review: Genetics, Dennis M. Sullivan
Book Review: The Language of God, Dennis M. Sullivan
Making Sense of the Stem Cell Controversy, Dennis M. Sullivan
Reproductive Technologies 101, Dennis M. Sullivan
Under the Night Sky, Dennis M. Sullivan
Gene Therapy: Restoring Health or Playing God?, Dennis M. Sullivan and Susan A. Salladay
Sorting Through the Stem Cell Hype, Dennis M. Sullivan and Kathy Schoonover-Shoffner
Becoming an Exceptional Ohio Preceptor: More Than Being Experienced, Marc A. Sweeney
The Ubiquitin Ligase gp78 Promotes Sarcoma Metastasis by Targeting KAI1 for Degradation, Yien Che Tsai, Arnulfo Mendoza, Jennifer M Mariano, Ming Zhou, Zlatka Kostova, Bo Chen, Timothy D. Veenstra, Stephen M. Hewitt, Lee J. Helman, Chand Khanna, and Allan M. Weissman
The Protein Kinase C-η Isoform Induces Proliferation in Glioblastoma Cell Lines Through an ERK/Elk-1 Pathway, R. M. Uht, Samson Amos, P. M. Martin, A. E. Riggan, and Isa M. Hussaini
Global and Targeted Quantitative Proteomics for Biomarker Discovery, Timothy D. Veenstra
Analysis of the Extracellular Matrix Vesicle Proteome in Mineralizing Osteoblasts, Zhen Xiao, Corinne E. Camalier, Kunio Nagashima, King C. Chan, David A. Lucas, M. Jason de la Cruz, Michelle Gignac, Stephen Lockett, Haleem J. Issaq, Timothy D. Veenstra, and et al
A Liquid Chromatography-Mass Spectrometry Method for the Quantitative Analysis of Urinary Endogenous Estrogen Metabolites, Xia Xu, Larry K. Keefer, Regina G. Ziegler, and Timothy D. Veenstra
Quantitative Measurement of Endogenous Estrogens and Estrogen Metabolites in Human Serum by Liquid Chromatography-Tandem Mass Spectrometry, Xia Xu, John M. Roman, Haleem J. Issaq, Larry K. Keefer, Timothy D. Veenstra, and Regina G. Ziegler
Quantitative Proteomic Analysis of Human Breast Epithelial Cells with Differential Telomere Length, Li-Rong Yu, King C. Chan, Hidetoshi Tahara, David A. Lucas, Koushik Chatterjee, Haleem J. Issaq, and Timothy D. Veenstra
Phosphoproteomics for the Discovery of Kinases as Cancer Biomarkers and Drug Targets, Li-Rong Yu, Haleem J. Issaq, and Timothy D. Veenstra
AACR–FDA–NCI Cancer Biomarkers Collaborative, Li-Rong Yu and Timothy D. Veenstra
Improved Titanium Dioxide Enrichment of Phosphopeptides from HeLa Cells and High Confident Phosphopeptide Identification by Cross-Validation of MS/MS and MS/MS/MS Spectra, Li-Rong Yu, Zhongyu Zhu, King C. Chan, Haleem J. Issaq, Dimiter S. Dimitrov, and Timothy D. Veenstra
Detection of In Vitro Kinase Generated Protein Phosphorylation Sites Using Gamma[18O4]-ATP and Mass Spectrometry, Ming Zhou, Zhaojing Meng, Andrew G. Jobson, Yves Pommier, and Timothy D. Veenstra
Proteomic Analysis of Protein Complexes, Ming Zhou and Timothy D. Veenstra
Proteomic Analysis of Protein Complexes, M. Zhou and Timothy D. Veenstra
Publications from 2006
Depression in Older Adults: The Case of an 82-year-old Woman with Dizziness, Ali Ahmed, Mark J. Yaffe, Phillip L. Thornton, and F. Cleveland Kinney
Plasma Proteomic Profiling: Search for Lung Cancer Diagnostic and Early Detection Markers, Iqbal Unnisa Ali, Zhen Xiao, Winfred Malone, Mylinh Smith, Thomas P. Conrads, Timothy D. Veenstra, Peter Greenwald, Brian T. Luke, and Jerry W. McLarty
Protein Kinase C-α Mediated Downregulation of Low-Density Lipoprotein Receptor-related Protein Expression Increases Urokinase Secretion and Astrocytoma Invasion, Samson Amos and Isa M. Hussaini
Farnesylthiosalicylic Acid Induces Caspase Activation and Apoptosis in Glioblastoma Cells, Samson Amos, G. T. Redpath, G. Polar, R. McPheson, D. Schiff, and I. M. Hussaini
Serevent, Advair, and the Black Box Warning, Douglas C. Anderson
Vancomycin Shortage, Douglas C. Anderson
A Survey to Determine Influences on Pharmacy Students' Choice of Pharmacy as a Major, Douglas C. Anderson, M. C. Sheffield, A. M. Massey, and H. H. Cobb
Direct Phosphorylation and Activation of a Nim1-Related Kinase Gin4 by Elm1 in Budding Yeast, Satoshi Asano, Jung-Eun Park, Li-Rong Yu, Ming Zhou, Krisada Sakchaisri, Chong J. Park, Young H. Kang, Jeremy Thorner, Timothy D. Veenstra, and Kyung S. Lee
The Effects of Methimazole on Circulating Thyroid Hormone Levels in Sprague-Dawley Rats, Melissa J. Beck, D. A. Donahue, J. S. Varsho, M. D. Nemec, D. G. Stump, and J. F. Holson
The Ontogeny of Circulating Thyroid Hormone Levels in Sprague-Dawley Rats, Melissa J. Beck, H. Fillutzy, J. Godsey, M. D. Nemec, D. G. Stump, and J. F. Holson
A Pre- and Postnatal Study of Bicifadine HCl in Rats, Melissa J. Beck, J. P. Tizzano, P. A. Krieter, S. Ho, D. W. Sved, and J. Buelke-Sam
Identification of Membrane Proteins From Mammalian Cell/Tissue Using Methanol-Facilitated Solubilization and Tryptic Digestion Coupled with 2D-LC-MS/MS, Josip Blonder, King C. Chan, Haleem J. Issaq, and Timothy D. Veenstra
Proteomic Profiling of Differentiating Osteoblasts, Josip Blonder, Zhen Xiao, and Timothy D. Veenstra
Combined Chemical and Enzymatic Stable Isotope Labeling for Quantitative Profiling of Detergent-Insoluble Membrane Proteins Isolated Using Triton X-100 and Brij-96, Josip Blonder, Li-Rong Yu, Galina Radeva, King C. Chan, David A. Lucas, Timothy J. Waybright, Haleem J. Issaq, Frances J. Sharom, and Timothy D. Veenstra
Proteomic and Biochemical Analysis of Purified Human Immunodeficiency Virus Type 1 Produced from Infected Monocyte-Derived Macrophages, Elena Chertova, Lori V. Coren, James D. Roser, Charles M. Trubey, Raymond C. Sowder, Eugene Barsov, Brian L. Hood, Robert J. Fisher, Thomas P. Conrads, Timothy D. Veenstra, and et al
Mass Spectrometric Characterization of Post-Translational Modifications, Thomas P. Conrads, Brian L. Hood, and Timothy D. Veenstra
Sampling and Analytical Strategies for Biomarker Discovery Using Mass Spectrometry, Thomas P. Conrads, Brian L. Hood, and Timothy D. Veenstra
CKAP4/p63 is a Receptor for the Frizzled-8 Protein-Related Antiproliferative Factor from Interstitial Cystitis Patients, Thomas P. Conrads, Gillian M. Tocci, Brian L. Hood, Chen-Ou Zhang, Li Guo, Kristopher R. Koch, Christopher J. Michejda, Timothy D. Veenstra, and Susan K. Keay
2-Cyano-3,12-Dioxooleana-1,9(11)-Diene-28-Oic Acid Disrupts Microtubule Polymerization: A Possible Mechanism Contributing to Apoptosis, Robin D. Couch, Neil J. Ganem, Ming Zhou, Veljko M. Popov, Tadashi Honda, Timothy D. Veenstra, Michael B. Sporn, and Amy C. Anderson
Let the Adventure Begin, Marty L. Eng
Open-Label Trial Regarding the Use of Acupuncture and Yin Tui Na in Parkinson's Disease Outpatients: A Pilot Study on Efficacy, Tolerability, and Quality of Life, Marty L. Eng, K. E. Lyons, M. S. Greene, and R. Pahwa
Prevalence of Bone Mineral Density Screening in Parkinson Disease Clinic Outpatients, Marty L. Eng, Kelly E. Lyons, and Rajesh Pahwa
Polo-Like Kinase 1-Mediated Phosphorylation of the GTP-Binding Protein Ran is Important for Bipolar Spindle Formation, Yang Feng, Jin Hui Yuan, Sharon C. Maloid, Rebecca Fisher, Terry D. Copeland, Dan L. Longo, Thomas P. Conrads, Timothy D. Veenstra, Andrea Ferris, Steve Hughes, Dimiter S. Dimitrov, and Douglass K. Ferris
Mass Spectrometry Reveals Specific and Global Molecular Transformations during Viral Infection, Eden P. Go, William R. Wikoff, Zhouxin Shen, Grace O'Maille, Hirotoshi Morita, Thomas P. Conrads, Anders Nordstrom, Sunia A. Trauger, Wilasinee Uritboonthai, Timothy D. Veenstra, and et al
Regulation of Androgen Receptor Activity by Tyrosine Phosphorylation, Zhiyong Guo, Bojie Dai, Tianyun Jiang, Kexin Xu, Yingqiu Xie, Oekyung Kim, Issa Nesheiwat, Xiangtian Kong, Jonathan Melamed, Venkatesh D. Handratta, Vincent C.O. Njar, Angela M.H. Brodie, Li-Rong Yu, Timothy D. Veenstra, Hegang Chen, and Yun Qiu
Cytokinesis Regulator ECT2 Changes its Conformation Through Phosphorylation at Thr-341 in G2/M Phase, T. Hara, M. Abe, H. Inoue, L.R. Yu, Timothy D. Veenstra, Y. H. Kang, K. S. Lee, and T. Miki
A Validation of Place Preference Conditioning to Measure the Rewarding Properties of Drugs in Rats, M. T. Herberth, P. B. Bucci, C. Hutchison, Melissa J. Beck, M. D. Nemec, and G. J. Schaefer
Seniors' Attitudes and Knowledge About Medicare Part D, Aleda M. Hess and D. L. Sullivan
Mass Spectrometric Analysis of Formalin-Fixed Paraffin-Embedded Tissue: Unlocking the Proteome Within, Brian L. Hood, Thomas P. Conrads, and Timothy D. Veenstra
Unravelling the Proteome of Formalin-Fixed Paraffin-Embedded Tissue, Brian L. Hood, Thomas P. Conrads, and Timothy D. Veenstra
Self-Regulated Plk1 Recruitment to Kinetochores by the Plk1-PBIP1 Interaction is Critical for Proper Chromosome Segregation, Young H. Kang, Jung-Eun Park, Li-Rong Yu, Nak-Kyun Soung, Sang-Moon Yun, Jeong K. Bang, Yeon-Sun Seong, Hongtao Yu, Susan Garfield, Timothy D. Veenstra, and Kyung S. Lee
Increased Oxidation and Degradation of Cytosolic Proteins in Alcohol-Exposed Mouse Liver and Hepatoma Cells, Bong-Jo Kim, Brian L. Hood, Richard A. Aragon, James P. Hardwick, Thomas P. Conrads, Timothy D. Veenstra, and Byoung J. Song
Potential Applications and Limitations of Proteomics in the Study of Neurological Disease, Yoshito Kinoshita, Takuma Uo, Suman Jayadev, Gwenn A. Garden, Thomas P. Conrads, Timothy D. Veenstra, and Richard S. Morrison
Proteomics in Models of Neurodegeneration, Y. Kinoshita, T. Uo, T. P. Conrads, Timothy D. Veenstra, and R. S. Morrison
Deamidation of Peptides in Aerobic Nitric Oxide Solution by a Nitrosative Pathway, Li Kong, Joseph E. Saavedra, Gregory S. Buzard, Xia Xu, Brian L. Hood, Thomas P. Conrads, Timothy D. Veenstra, and Larry K. Keefer
Probing Early Growth Response 1 Interacting Proteins at the Active Promoter in Osteoblast Cells Using Oligoprecipitation and Mass Spectrometry, Zhaojing Meng, Corinne E. Camalier, David A. Lucas, Timothy D. Veenstra, George R. Beck, and Thomas P. Conrads
Inactivation of Oxidized and S-Nitrosylated Mitochondrial Proteins in Alcoholic Fatty Liver of Rats, Kwan-Hoon Moon, Brian L. Hood, Bong-Jo Kim, James P. Hardwick, Thomas P. Conrads, Timothy D. Veenstra, and Byoung J. Song
Identification of Sokotrasterol Sulfate as a Novel Proangiogenic Steroid, Siun Murphy, Bruno Larrivée, Ingrid Pollet, Kyle S. Craig, David E. Williams, Xin-Hui Huang, Megan Abbott, Fred Wong, Cameron Curtis, Timothy D. Veenstra, and et al
Proteomic Analysis of Plasma Membrane from Hypoxia-Adapted Malignant Melanoma, Luke H. Stockwin, Josip Blonder, Maja A. Bumke, David A. Lucas, King C. Chan, Thomas P. Conrads, Haleem J. Issaq, Timothy D. Veenstra, Dianne L. Newton, and Susanna M. Rybak
End of Life Decisions 101, Dennis M. Sullivan
Stem Cell Research and Moral Complicity, Dennis M. Sullivan
Stem Cells 101, Dennis M. Sullivan
The Oral Contraceptive as Abortifacient: An Analysis of the Evidence, Dennis M. Sullivan
Avoid Medicine Mishaps, Marc A. Sweeney and D. Conway
Automation in Proteomics, Timothy D. Veenstra
Mass Spectrometry: The Foundation of Proteomics, Timothy D. Veenstra
Proteomic Approaches in Drug Discovery, Timothy D. Veenstra
LC‐MS in Metabonomics: Optimization of Experimental Conditions for the Analysis of Metabolites in Human Urine, Timothy J. Waybright, Que N. Van, Gary M. Muschik, Thomas P. Conrads, Timothy D. Veenstra, and Haleem J. Issaq
Chronic Hypoxic Decreases in Soluble Guanylate Cyclase Protein and Enzyme Activity are Age Dependent in Fetal and Adult Ovine Carotid Arteries, James M. Williams, Charles R. White, Melody M. Chang, Elisha R. Injeti, Lubo Zhang, and William J. Pearce
Analysis of Fifteen Estrogen Metabolites Using Packed Column Supercritical Fluid Chromatography-Mass Spectrometry, Xia Xu, John M. Roman, Timothy D. Veenstra, Jennifer Van Anda, Regina G. Ziegler, and Haleem J. Issaq
Parallel Analysis of Transcript and Translation Profiles: Identification of Metastasis-Related Signal Pathways Differentially Regulated by Drug and Genetic Modifications, Haiyan Yang, Li-Rong Yu, Ming Yi, David A. Lucas, Luanne Lukes, Mindy Lancaster, King C. Chan, Haleem J. Issaq, Robert M. Stephens, Timothy D. Veenstra, and et al
Identification of the SELDI ProteinChip Human Serum Retentate by Microcapillary Liquid Chromatography-Tandem Mass Spectrometry, Ming Zhou, DaRue A. Prieto, David A. Lucas, King C. Chan, Haleem J. Issaq, Timothy D. Veenstra, and Thomas P. Conrads
Multiplexed Immunofluorescence Microscopy for the Interrogation of Cellular Protein Complexes, Ming Zhou and Timothy Veenstra
Publications from 2005
Phorbol 12-Myristate 13-Acetate Induces Epidermal Growth Factor Receptor Transactivation via Protein Kinase Cdelta/c-Src Pathways in Glioblastoma Cells, Samson Amos, Patrick M. Martin, Gregory A. Polar, Sarah J. Parsons, and Isa M. Hussaini
ACEI and ARB Conversion, Douglas C. Anderson
Herbal Medicines: Myths, Truths, and Clinical Trials, Douglas C. Anderson
Pharmacologic Prevention or Delay of Type 2 Diabetes Mellitus, Douglas C. Anderson
Concerted Mechanism of Swe1/Wee1 Regulation by Multiple Kinases in Budding Yeast, Satoshi Asano, Jung-Eun Park, Krisada Sakchaisri, Li-Rong Yu, Sukgil Song, Porntip Supavilai, Timothy Veenstra, and Kyung S. Lee
Predicting Inhibitory Drug—Drug Interactions and Evaluating Drug Interaction Reports Using Inhibition Constants, Kenneth A. Bachmann and Jeffrey D. Lewis
A Method for Simultaneous Whole-Body Inhalational (Inh.) Exposure of Lactating Rats and Offspring, Melissa J. Beck, M. D. Nemec, D Kirkpatrick, J. F. Holson, S. A. Lewis, V. J. Piccirillo, and D. McAllister
Quantitative Profiling of the Detergent-Resistant Membrane Proteome of Iota-B Toxin Induced Vero Cells, Josip Blonder, Martha L. Hale, King C. Chan, Li-Rong Yu, David A. Lucas, Thomas P. Conrads, Ming Zhou, Michel R. Popoff, Haleem J. Issaq, Timothy D. Veenstra, and et al
Low Molecular Weight Proteomic Information Distinguishes Metastatic from Benign Pheochromocytoma, F. M. Brouwers, E. F. Petricoin, L. Ksinantova, J. Breza, V. Rajapakse, S. Ross, D. Johann, M. Mannelli, B. L. Shulkin, Timothy D. Veenstra, and et al
Enrichment of Low-Molecular-Weight Proteins from Biofluids for Biomarker Discovery, Oleg Chertov, John T. Simpson, Arya Biragyn, Thomas P. Conrads, Timothy D. Veenstra, and Robert J. Fisher
A Combined Proteome and Microarray Investigation of Inorganic Phosphate-Induced Pre-Osteoblast Cells, Kelly A. Conrads, Ming Yi, Kerri A. Simpson, David A. Lucas, Corinne E. Camalier, Li-Rong Yu, Timothy D. Veenstra, Robert M. Stephens, Thomas P. Conrads, and George R. Beck
Cancer Proteomics: Many Technologies, One Goal, Thomas P. Conrads, Brian L. Hood, Emmanuel F. Petricoin, Lance A. Liotta, and Timothy D. Veenstra
What Have We Learned from Proteomic Studies of Serum?, Thomas P. Conrads and Timothy D. Veenstra
Mass Spectrometry Based Proteomic Approaches for Disease Diagnosis and Biomarker Discovery, T. P. Conrads, H. J. Issaq, J. Blonder, and Timothy D. Veenstra
