Pharmacy Faculty Publications

 

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Publications from 2003

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Palliative Care in Heart Failure, Ali Ahmed and Phillip L. Thornton

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Hypotensive Activity of the Ethanol Extract of Pavetta crassipes Leaves, Samson Amos, Peter Achunike Akah, Lucy Binda, Nkechi Mercy Enwerem, Abiodun Ogundaini, Charles Wambebe, Isa Marte Hussaini, and Karniyus Shingu Gamaniel

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Effect of the Aqueous Extract of Chrysanthellum indicum on Calcium Mobilization and Activation of Rat Portal Vein, Samson Amos, L. Binda, M. Adamu, H. O. Vongtau, J. Abbah, E. K. I. Omogbai, P. A. Akah, B. B. Bukar, C. Wambebe, and K. Gamaniel

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Central Inhibitory Activity of the Aqueous Extract of Crinum giganteum, Samson Amos, L. Binda, P. Akah, C. Wambebe, and K. Gamaniel

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Neuropharmacological Effects of Hibiscus sabdariffa Aqueous Extract, Samson Amos, L. Binda, B. A. Chindo, A. Tseja, C. Wambebe, and K. Gamaniel

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Smooth Muscle Contraction Induced by Indigofera dendroides Leaf Extracts May Involve Calcium Mobilization via Potential Sensitive Channels, Samson Amos, L. Binda, O. F. Kunle, I. Okafor, M. Emeje, P. A. Akah, C. Wambebe, and K. Gamaniel

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Postsynaptic Dopamine (D2)-mediated Behavioural Effects of High Acute Doses of Artemisinin in Rodents, Samson Amos, B. A. Chindo, J. Abbah, H. O. Vongtau, I. Edmond, L. Binda, P. A. Akah, C. Wambebe, and K. S. Gamaniel

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Continuous Infusion as a Route of Administration in Embryo/Fetal Development Studies in the Rabbit, Melissa J. Beck, T. R. Gleason, C. S. Wally, C. P. Chengelis, D. G. Stump, and M. D. Nemec

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Developmental Toxicity Studies in Rats and Rabbits with DOV 21,947: A Triple Reuptake Inhibitor, Melissa J. Beck, D. G. Stump, M. D. Nemec, J. F. Holson, J. P. Tizzano, and J. Buelke-Sam

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Central Nervous System Activity of the Methanol Extract of Ficus platyphylla Stem Bark, B. A. Chindo, Samson Amos, A. A. Odutola, H. O. Vongtau, J. Abbah, C. Wambebe, and K. S. Gamaniel

Cancer Diagnosis Using proteomic Patterns, Thomas P. Conrads, Ming Zhou, Emmanuel F. Petricoin, Lance Liotta, and Timothy D. Veenstra

Ohio Northern University Students Bringing Information to the Community, K. DeNucci, M. Dorsch, and Marc A. Sweeney

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A Comparison of MicroLC/Electrospray Ionization-MS and GC/MS for the Measurement of Stable Isotope Enrichment from a [2H2]-Glucose Metabolic Probe in T-Cell Genomic DNA, S. D. Fox, R. A. Lempicki, D. A. Hosack, M. W. Baseler, J. A. Kovacs, H. C. Lane, Timothy D. Veenstra, and H. J. Issaq

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VFEND (Voriconazole), Aigner George, Miriam A. Ansong, and Maurice W. Landers Jr.

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Preinvasive and Invasive Ductal Pancreatic Cancer and its Early Detection in the Mouse, Sunil R. Hingorani, Emanuel F. Petricoin, Anirban Maitra, Vinodh Rajapakse, Catrina King, Michael A. Jacobetz, Sally Ross, Thomas P. Conrads, Timothy D. Veenstra, Ben A. Hitt, and et al

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Quantitative Proteomics Employing Primary Amine Affinity Tags, Van M. Hoang, Thomas P. Conrads, Timothy D. Veenstra, Josip Blonder, Atsushi Terunuma, Jonathan C. Vogel, and Robert J. Fisher

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Peer Reviewed: SELDI-TOF MS for Diagnostic Proteomics, Haleem J. Issaq, Thomas P. Conrads, DaRue A. Prieto, Radhakrishna Tirumalai, and Timothy D. Veenstra

Proteomic Patters: A Potential Test for Early Diagnosis of Ovarian Cancer, Haleem J. Issaq, Thomas P. Conrads, and Timothy D. Veenstra

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Effect of Experimental Parameters on the HPLC Separation of Peptides and Proteins, Haleem J. Issaq, Stephen D. Fox, Megha Mahadevan, Thomas P. Conrads, and Timothy D. Veenstra

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Development of a Two-Dimensional Protein-Peptide Separation Protocol for Comprehensive Proteome Measurements, George M. Janini, Thomas P. Conrads, Timothy D. Veenstra, and Haleem J. Issaq

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Development of a Two-Dimensional Protein-Peptide Separation Protocol for Comprehensive Proteome Measurements, George M. Janini, Thomas P. Conrads, Timothy D. Veenstra, and Haleem J. Issaq

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A Sheathless Nanoflow Electrospray Interface for On-Line Capillary Electrophoresis Mass Spectrometry, George M. Janini, Thomas P. Conrads, Kenneth L. Wilkens, Haleem J. Issaq, and Timothy D. Veenstra

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On-Column Sample Enrichment for Capillary Electrophoresis Sheathless Electrospray Ionization Mass Spectrometry: Evaluation for Peptide Analysis and Protein Identification, George M. Janini, Ming Zhou, Li-Rong Yu, Josip Blonder, Michelle Gignac, Thomas P. Conrads, Haleem J. Issaq, and Timothy D. Veenstra

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Novel Approaches to Visualization and Data Mining Reveals Diagnostic Information in the Low Amplitude Region of Serum Mass Spectra from Ovarian Cancer Patients, Donald J. Johann, Michael D. McGuigan, Stanimire Tomov, Vincent A. Fusaro, Sally Ross, Thomas P. Conrads, Timothy D. Veenstra, David A. Fishman, Gordon R. Whiteley, Emanuel F. Petricoin, and Lance A. Liotta

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Anti-Angiogenic Activity of Human Endostatin is HIF-1-Independent in Vitro and Sensitive to Timing of Treatment in a Human Saphenous Vein Assay, Gordon R. Macpherson, Sylvia S.W. Ng, Siiri L. Forbes, Giovanni Melillo, Tatiana Karpova, James McNally, Thomas P. Conrads, Timothy D. Veenstra, Alfredo Martinez, Frank Cuttitta, and et al

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Reminyl (Galantamine Hbr), Jeannette S. McWhorter, Miriam A. Ansong, and Maurice W. Landers Jr.

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Protein Phosphatase 2A Positively Regulates Ras Signaling by Dephosphorylating KSR1 and Raf-1 on Critical 14-3-3 Binding Sites, Stéphane Ory, Ming Zhou, Thomas P. Conrads, Timothy D. Veenstra, and Deborah K. Morrison

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1,3-Dinitrobenzene Inhibits Mitochondrial Complex II in Rat and Mouse Brainstem and Brainstem and Cortical Astrocytes, A. D. Phelka, Melissa J. Beck, and M. A. Philbert

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Profiling of Secreted Proteins from Human Ovarian Cancer Cell Lines by Surface-Enhanced Laser Desorption Ionization Time-of-Flight Mass Spectrometry, DaRue Prieto, Thomas P. Conrads, Dominic A. Scudiero, Timothy D. Veenstra, and Haleem J. Issaq

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Do Nursing Home Residents have Lower Rates of Inappropriate Medication Use than their Community-dwelling Frail Elder Peers?, Sally K. Rigler, Theresa I. Shireman, Carolyn M. Jachna, and Marty L. Eng

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Pharmacologic Management by Clinical Pharmacists of Behavioral and Psychological Symptoms of Dementia in Nursing Home Residents: Results from a Pilot Study, Carlos H. Rojas-Fernandez, Marty L. Eng, and Nicole D. Allie

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High-Performance Separations and Mass Spectrometric Methods for High-Throughput Proteomics using accurate Mass Tags, Richard D. Smith, Gordon A. Anderson, Mary S. Lipton, Christophe Masselon, Ljiljana Paša-Tolic, Harold Udseth, Mikhail Belov, Yufeng Sheng, and Timothy D. Veenstra

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Zetia (Ezetimibe), Jennifer Stuck, Miriam A. Ansong, and Maurice W. Landers Jr.

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The Conception View of Personhood: A Review, Dennis M. Sullivan

Towards a Holistic Approach to Design, Dennis M. Sullivan

Alzheimer’s Disease, Phillip L. Thornton

Delirium and Dementia, Phillip L. Thornton

Seizure Disorders, Phillip L. Thornton

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Characterization of the Low Molecular Weight Human Serum Proteome, Radhakrishna S. Tirumalai, King C. Chan, DaRue A. Prieto, Haleem J. Issaq, Thomas P. Conrads, and Timothy D. Veenstra

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The Depletion of Protein Signals in Metabonomics Analysis with the WET-CPMG Pulse Sequence, Que N. Van, Gwendolyn N. Chmurny, and Timothy D. Veenstra

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The Use of Urine Proteomic and Metabonomic Patterns for the Diagnosis of Interstitial Cystitis and Bacterial Cystitis, Que N. Van, John R. Klose, David A. Lucas, DaRue A. Prieto, Brian Luke, Jack Collins, Stanley K. Burt, Gwendolyn N. Chmurny, Haleem J. Issaq, Thomas P. Conrads, Timothy D. Veenstra, and Susan K. Keay

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Proteome Analysis of Posttranslational Modifications, Timothy D. Veenstra

Serum Protein Fingerprinting, Timothy D. Veenstra and Thomas P. Conrads

Phosphoproteomics, Timothy D. Veenstra and T. P. Conrads

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Forteo (Teriparatide), Yolanda D. Williams, Miriam A. Ansong, and Maurice W. Landers Jr.

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Evaluation of Liquid Chromatography–Mass Spectrometry for Routine Proteome Analyses, Li-Rong Yu, Haleem J. Issaq, Thomas P. Conrads, Takuma Uo, Josip Blonder, George m. Janini, Richard S. Morrison, and Timothy D. Veenstra

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Diagnostic Proteomics: Serum Proteomic Patterns for the Detection of Early Stage Cancers, Li-Rong Yu, Ming Zhou, Thomas P. Conrads, and Timothy D. Veenstra

New Tools for Quantitative Phosphoproteome Analysis, L. R. Yu and Timothy D. Veenstra

Publications from 2002

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Pharmacological Evidence Favouring the Folkloric Use of Diospyros mespiliformis Hochst in the Relief of Pain and Fever, B. Adzu, Samson Amos, S. Dzarma, I. Muazzam, and K. S. Gamaniel

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Effect of Zizyphus spina-christi Willd Aqueous Extract on the Central Nervous System in Mice, B. Adzu, Samson Amos, S. Dzarma, C. Wambebe, and K. Gamaniel

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Neuropharmacological Screening of Diospyros mespiliformis in Mice, B. Adzu, Samson Amos, I. Muazzam, U. S. Inyang, and K. S. Gamaniel

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Behavioural Effects in Rodents of Methyl Angolensate: a Triterpenoid Isolated from Entandrophragma angolense, Samson Amos, Orisadipe Abayomi, Lucy Binda, Emeje Martins, Adesomoju Akinbobola, Joseph Okogun, Peter Akah, Charles Wambebe, and Karniyus Gamaniel

Preliminary Studies on Anti-inflammatory and Anti-nociceptive Effects of the Aqueous Extract of Chrysanthellum indicum, Samson Amos, M. Adamu, L. Binda, I. Edmond, O. F. Kunle, P. Akah, C. Wambebe, and K. Gamaniel

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Uterotonic Properties of the Ethanol Extract of Brysocarpus coccineus, Samson Amos, L. Binda, O. F. Kunle, C. Wambebe, and K. Gamaniel

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Anti-Inflammatory and Anti-Nociceptive Effects of Ficus platyphylla Extract in Mice and Rats, Samson Amos, B. A. Chindo, I. Edmond, P. Akah, C. Wambebe, and K. Gamaniel

Supernaw R. Pain Management Part III: Assessment and Monitoring of Pain Therapy, Douglas C. Anderson

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Starlix (Nateglinide), Miriam A. Ansong, Katrinia R. Bell, and Maurice W. Landers Jr.

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Frova (Frovatriptan Succinate), Miriam A. Ansong and Maurice W. Landers Jr.

Validation of Peripheral Tissue Cholinesterase Activity Assessment in Rats Administered Chlorpyrifos by Gavage, Melissa J. Beck, M. D. Nemec, G. J. Schaefer, D. G. Stump, and J. Buelke-Sam

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Low-Energy Collision-Induced Dissociation Fragmentation Analysis of Cysteinyl-Modified Peptides, Oleg V. Borisov, Michael B. Goshe, Thomas P. Conrads, V. Sergey Rakov, Timothy D. Veenstra, and Richard D. Smith

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An Accurate Mass Tag Strategy for Quantitative and High Throughput Proteome Measurements, Thomas P. Conrads, Haleem J. Issaq, and Timothy D. Veenstra

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New Tools for Quantitative Phosphoproteome Analysis, Thomas P. Conrads, Haleem J. Issaq, and Timothy D. Veenstra

High-Throughput, Quantitative Proteomics of Intact and Proteolytically Digested Proteins, T. P. Conrads, G. A. Anderson, D. J. Anderson, M. E. Belov, R. Harkewicz, M. S. Lipton, C. Masselon, L. Paša-Tolic, Y. Shen, H. R. Udseth, R. D. Smith, and Timothy D. Veenstra

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Phosphoprotein Isotope-Coded Affinity Tags: Application to the Enrichment and Identification of Low-Abundance Phosphoproteins, Michael B. Goshe, Timothy D. Veenstra, Ellen A. Panisko, Thomas P. Conrads, Nicolas H. Angell, and Richard D. Smith

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Methods for Fractionation, Separation and Profiling of Proteins and Peptides, Haleem J. Issaq, Thomas P. Conrads, George M. Janini, and Timothy D. Veenstra

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The SELDI-TOF MS Approach to Proteomics: Protein Profiling and Biomarker Identification, Haleem J. Issaq, Timothy D. Veenstra, Thomas P. Conrads, and Donna Felschow

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Selective Incorporation of Isotopically Labeled Amino Acids for Identification of Intact Proteins on a Proteome-Wide Level, Suzana Martinović, Timothy D. Veenstra, Gordon A. Anderson, Ljiljana Pasa-Tolić, and Richard D. Smith

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Proteomic Analysis in the Neurosciences, Richard S. Morrison, Yoshito Kinoshita, Mark D. Johnson, Takuma Uo, Joseph T. Ho, Joshua K. McBee, Thomas P. Conrads, and Timothy D. Veenstra

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The Postgenomic Age: Characterization of Proteomes, Ellen A. Panisko, Thomas P. Conrads, Michael B. Goshe, and Timothy D. Veenstra

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Potential Role of Mitochondrial Complex II in the Differential CNS Sensitivity to 1,3-Dinitrobenzene-Induced Encephalopathy, A. D. Phelka, Melissa J. Beck, and M. A. Philbert

Advanced Mass Spectrometric Approaches for Rapid and Quantitative Proteomics, R. D. Smith, G. A. Anderson, P. K. Jensen, M. S. Lipton, L. Paša-Tolic, and Timothy D. Veenstra

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An Accurate Mass Tag Strategy for Quantitative and High-Throughput Proteome Measurements, Richard D. Smith, Gordon A. Anderson, Mary S. Lipton, Ljiljana Pasa-Tolic, Yufeng Shen, Thomas P. Conrads, Timothy D. Veenstra, and Harold R. Udseth

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Physician-Pharmacist Collaboration: A Millennial Paradigm to Reduce Medication Errors, Marc A. Sweeney

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A Method to Evaluate Tryptic Digestion Efficiency for High-Throughput Proteome Analyses, Susan K. Wierenga, Mark J. Zocher, Matthew M. Mirus, Thomas P. Conrads, Michael B. Goshe, and Timothy D. Veenstra

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Proteome Analysis of Camptothecin-Treated Cortical Neurons Using Isotope-Coded Affinity Tags, Li-Rong Yu, Mark D. Johnson, Thomas P. Conrads, Richard D. Smith, Richard S. Morrison, and Timothy D. Veenstra

Publications from 2001

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Antidiarrhoeal Activity of the Aqueous Extract of Terminalia avicennoides Roots, A. L. Abdullahi, M. O. Agho, Samson Amos, K. S. Gamaniel, and C. Wambebe

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Antinociceptive Activity of Zizyphus spina-christi Root Bark Extract, B. Adzu, Samson Amos, C. Wambebe, and K. Gamaniel

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Neuropharmacological Effect of the Aqueous Extract of Sphaeranthus senegalensis in Mice, Samson Amos, B. Adzu, L. Binda, C. Wambebe, and K. Gamaniel

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Cardiovascular Effects of the Aqueous Extract of Chrysanthellum indicum, Samson Amos, L. Binda, M. Adamu, C. Wambebe, and K. Gamaniel

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Behavioral Effects of the Aqueous Extract of Guiera senegalensis in Mice and Rats, Samson Amos, E. Kolawole, P. Akah, C. Wambebe, and K. Gamaniel

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Mitochondria in Migrating Neural Crest Cells are Sensitive to Ethanol-Induced Loss of Mitochondrial Transmembrane Potential, Melissa J. Beck, C. Harris, and M. A. Philbert

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Spatial Glutathione and Cysteine Distribution and Chemical Modulation in the Early Organogenesis Stage Rat Conceptus In Utero, Melissa J. Beck, C. McLellan, R. L.-F. Lightle, M. A. Philbert, and C. Harris

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Design and Performance of an ESI Interface for Selective External Ion Accumulation Coupled to a Fourier Transform Ion Cyclotron Mass Spectrometer, Mikhail E. Belov, Evgenii N. Nikolaev, Gordon A. Anderson, Harold R. Udseth, Thomas P. Conrads, Timothy D. Veenstra, Christophe D. Masselon, Mikhail V. Gorshkov, and Richard D. Smith

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Pharmacological Activity of the Methanolic Extract of Cassia nigricans Leaves, F. C. Chidume, K. Gamaniel, Samson Amos, P. Akah, O. Obodozie, and C. Wambebe

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Quantitative Analysis of Bacterial and Mammalian Proteomes Using a Combination of Cysteine Affinity Tags and 15N-Metabolic Labeling, Thomas P. Conrads, Kim Alving, Timothy D. Veenstra, Mikhail E. Belov, Gordon A. Anderson, David J. Anderson, Mary S. Lipton, Lijliana Pasa-Tolić, Harold R. Udseth, William B. Chrisler, Brian D. Thrall, and Richard D. Smith

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Phosphoprotein Isotope-Coded Affinity Tag Approach for Isolating and Quantitating Phosphopeptides in Proteome-Wide Analyses, Michael B. Goshe, Thomas P. Conrads, Ellen A. Panisko, Nicolas H. Angell, Timothy D. Veenstra, and Richard D. Smith

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A New Squalene-derived Epoxy tri-THF diol from Spathelia glabrescens, Wayne W. Harding, Denise S. Simpson, Helen Jacobs, Stewart McLean, and William F. Reynolds

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Spasmolytic Activity of Methyl Angolensate: A Triterpenoid Isolated from Entandrophragma angolense, A. Orisadipe, Samson Amos, A. Adesomoju, L. Binda, M. Emeje, J. Okogun, C. Wambebe, and K. Gamaniel

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RNA-RNA Noncovalent Interactions Investigated by Microspray Ionization Mass Spectrometry, P. Rodrigues Hoyne, L. M. Benson, Timothy D. Veenstra, L. J. Maher, and S. Naylor

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Packed Capillary Reversed-Phase Liquid Chromatography with High-Performance Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for Proteomics, Yufeng Shen, Rui Zhao, Mikhail E. Belov, Thomas P. Conrads, Gordon A. Anderson, Keqi Tang, Ljiljana Pasa-Tolić, Timothy D. Veenstra, Mary S. Lipton, Harold R. Udseth, and Richard D. Smith

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Rapid Quantitative Measurements of Proteomes by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry, Richard D. Smith, Ljiljana Pasa-Tolić, Mary S. Lipton, Pamela K. Jensen, Gordon A. Anderson, Yufeng Shen, Thomas P. Conrads, Harold R. Udseth, Mikhail E. Belov, Timothy D. Veenstra, and et al

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A Thirty-Year Perspective on Personhood: How Has the Debate Changed?, Dennis M. Sullivan

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Common Sense Should Rule the Debate: Victims of ‘Partial-birth’ Abortion Sure Look Like Babies, Dennis M. Sullivan

The Need for Exceptions to Ethical Guidelines, Dennis M. Sullivan

Growth Hormone, Insulin-like Growth Factor-1, and the Aging Brain, Phillip L. Thornton and William E. Sonntag

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β-Amyloid-(1–42) Impairs Activity-dependent cAMP-response Element-binding Protein Signaling in Neurons at Concentrations in Which Cell Survival Is Not Compromised, Liqi Tong, Phillip L. Thornton, Robert Balazs, and Carl W. Cotman

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Antihypertensive Effect of Alpha- and Beta-Adrenergic Blockade in Obese and Lean Hypertensive Subjects, M. R. Wofford, Douglas C. Anderson, C. A. Brown, D. W. Jones, M. E. Miller, and J. E. Hall

Publications from 2000

Comparison of In Vitro and In Utero Ethanol Exposure on Indices of Oxidative Stress, S. A. Akella, Melissa J. Beck, M. A. Philbert, and C. Harris

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In Utero and In Vitro Comparison of Ethanol Effects on the Organogenesis Stage Rat Conceptus, S. A. Akella, Melissa J. Beck, M. A. Philbert, and C. Harris

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Pharmacological Effects of Aqueous Extract of the Chrysanthellum indicum on Gastrointestinal Smooth Muscles, Samson Amos, K. Gamaniel, M. Adamu, B. B. Bukar, P. Akah, and C. Wambebe